An integrative molecular and biological perspective on public health problems. Explores population biology and ecological principles underlying public health and reviews molecular biology in relation to public health biology. Modules focus on specific diseases of viral, bacterial, and environmental origin. Uses specific examples of each type to develop the general principles that govern interactions among susceptible organisms and etiologic agents. Devotes special attention to factors that act in reproduction and development. Places emphasis on common elements encountered in these modules. These may include origin and dissemination of drug resistance, organization and transmission of virulence determinants, modulation of immune responses, disruption of signal transduction pathways, and perturbation of gene expression.
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